-S, --local, --server=[//[domain/]][[#][@|[#]]
Specify IP address of upstream servers directly. Setting this flag does not suppress reading of /etc/resolv.conf, use -R to do that. If one or more optional domains are given, that server is used only for those domains and they are queried only using the specified server. This is intended for private nameservers: if you have a nameserver on your network which deals with names of the form xxx.internal.thekelleys.org.uk at 192.168.1.1 then giving the flag -S /internal.thekelleys.org.uk/192.168.1.1 will send all queries for internal machines to that nameserver, everything else will go to the servers in /etc/resolv.conf. DNSSEC validation is turned off for such private nameservers, UNLESS a --trust-anchor is specified for the domain in question. An empty domain specification, // has the special meaning of “unqualified names only” ie names without any dots in them. A non-standard port may be specified as part of the IP address using a # character. More than one -S flag is allowed, with repeated domain or ipaddr parts as required.
More specific domains take precedence over less specific domains, so: --server=/google.com/22.214.171.124 --server=/www.google.com/126.96.36.199 will send queries for *.google.com to 188.8.131.52, except *www.google.com, which will go to 184.108.40.206
The special server address ‘#’ means, “use the standard servers”, so --server=/google.com/220.127.116.11 --server=/www.google.com/# will send queries for *.google.com to 18.104.22.168, except *www.google.com which will be forwarded as usual.
So using the # on the same line is wrong.