How to block a part of domain?

Help
1

Hi, I use this program for the first time.
I would block only a part of the site.
For example I would block www.youtube.com/user/PewDiePie but I want to use youtube.
How Can I do?

2

This is impossible with a DNS based ad blocker because you can only block domains, not URLs.

3

Try adding Privoxy