Running the stock lists, I do not have any issues with either of these sites. The only domain being blocked I see in your debug log (and in my own stock lists) is script.ioam.de, but I am able to load the sites even with this domain blocked.
Will you try this:
Also, you may be running into this issue:
Many users have reported that frequently changing IPv6 addresses cause page load to be slow or even prevent from working at all. The issues can be fixed by updating the IPv6 address in /etc/pihole/setupVars.conf followed by a run of pihole -g.
However, this solution turns out to be very inconvenient since it might be necessary to change the IPv6 address on a regular basis (maybe even multiple times a day). An alternative approach we are currently looking into is the usage of ULA addresses which…