Hit:1 http://archive.raspberrypi.org/debian buster InRelease
Get:2 http://raspbian.raspberrypi.org/raspbian buster InRelease [15.0 kB]
Get:3 http://dl.mt-aws.com/debian/current wheezy InRelease [13.9 kB]
Get:4 http://raspbian.raspberrypi.org/raspbian buster/main Sources [11.4 MB]
Err:3 http://dl.mt-aws.com/debian/current wheezy InRelease
The following signatures were invalid: 2C00B003A56C5F2A75C44BF82A6E0307D0FF5699
Get:5 http://raspbian.raspberrypi.org/raspbian buster/main armhf Packages [13.0 MB]
Reading package lists... Done
W: GPG error: http://dl.mt-aws.com/debian/current wheezy InRelease: The following signatures were invalid: 2C00B003A56C5F2A75C44BF82A6E0307D0FF5699
E: The repository 'http://dl.mt-aws.com/debian/current wheezy InRelease' is not signed.
N: Updating from such a repository can't be done securely, and is therefore disabled by default.
N: See apt-secure(8) manpage for repository creation and user configuration details.
You will need to clean up your apt repositories. You are running a combination of Buster and Wheezy sources. Wheezy is way out of date (last supported years ago):
Debian 9.0 codename Stretch releases, Wheezy becomes oldoldstable (17 June 2017; 4 years ago)
Wheezy long term support reached end-of-life (1 June 2018; 3 years ago)
Wheezy extended long term support reached end-of-life (30 June 2020; 22 months ago)
Until apt update completes normally, the Pi-hole updater won't continue.
Thanks for the hint. Having commented the line within the file mt-aws.list in /etc/apt/sources.list.d directory that's pointing to a wheezy distribution has made the upgrade successful.