The FTL service should be running. The DNS service should be running.
I assume port 53 should not already be in use.
This is a Raspberry Pi 4, running the latest Raspberry Pi Desktop based on Debian 11 Bullseye, to which I upgraded yesterday. Today I switched it to the 64-bit version. I'm unable to pinpoint when pi-hole stopped working.
Actual Behaviour:
DNS service not running
DNSMASQ_CONFIG - FTL failed to start due to failed to create listening socket for port 53: Address already in use
FTL Information - The FTL service is offline!