This is the problem. Support for easy lists was dropped several versions ago (in Version 4.3.2, released September 2019), due to false positives. In Pi-hole V5 the gravity update script was re-rewritten, and some of the domains in the easy lists are being imported without the original context in the easy list. This is causing your false positives. You should not be using easy lists with Pi-hole - they are not the correct format.
Look at the following to demonstrate the problem:
Output of pihole -g
pihole -q github.com
The solution - drop the easy lists from your adlists. Use only lists provided in HOSTS format.