I did a search in the forums here and I did see a FAQ about the IPv4 combined with IPv6 false positives. I created the FTL conf file with the documented text and now those IPv6 instances are no longer shown in the query log, all I see are the Pi-holed IPv4 rcm-na.amazon-adsystems.com instances.
What happens to the IPv6 queries in reality? It's not clear to me where they're forwarded.
With that said, at this point the ad block result is purely cosmetic, I can see where the ad wanted to be, but it has no connection to load it. Is that the expected result? If I understand correctly, there is also a Google Ad on the page, but I've never seen that one or the spot on the page where it should be.