I/o timeout while coredns trying to access pihole-ftl

What does this error mean spotted while I was checking service status to fix some domains not opening without adding www.
My pihole dns is running on 5333 and coredns is front facing at 53.
journalctl -u coredns --since "1 min ago"

-- Logs begin at Sun 2020-12-06 19:21:37 GMT, end at Sat 2021-02-20 19:25:39 GMT. --
coredns[31405]: [ERROR] plugin/errors: 2 e16126.dscg.akamaiedge.net. A: read udp 192.168.5.165:45724->192.168.5.165:5333: i/o timeout
coredns[31405]: [ERROR] plugin/errors: 2 e16126.dscg.akamaiedge.net. A: read udp 192.168.5.165:60761->192.168.5.165:5333: i/o timeout
coredns[31405]: [ERROR] plugin/errors: 2 instagram.flhr1-1.fna.fbcdn.net. A: read udp 192.168.5.165:44018->192.168.5.165:5333: i/o timeout
coredns[31405]: [ERROR] plugin/errors: 2 instagram.flhr1-1.fna.fbcdn.net. A: read udp 192.168.5.165:44633->192.168.5.165:5333: i/o timeout
coredns[31405]: [ERROR] plugin/errors: 2 e16126.dscg.akamaiedge.net. A: read udp 192.168.5.165:51161->192.168.5.165:5333: i/o timeout
coredns[31405]: [ERROR] plugin/errors: 2 e16126.dscg.akamaiedge.net. A: read udp 192.168.5.165:36758->192.168.5.165:5333: i/o timeout
coredns[31405]: [ERROR] plugin/errors: 2 e16126.dscg.akamaiedge.net. A: read udp 192.168.5.165:46783->192.168.5.165:5333: i/o timeout
coredns[31405]: [ERROR] plugin/errors: 2 e16126.dscg.akamaiedge.net. A: read udp 192.168.5.165:48964->192.168.5.165:5333: i/o timeout

The issue I am facing:
Cannot access some domains without www. added

Details about my system:

  • Pi-hole [v5.2.1]
  • Web Interface [v5.2.1]
  • FTL [v5.3.2]
    Ubuntu 18.04

What I have changed since installing Pi-hole:
just noticed the issue pihole has ben running from few months.

Please provide some example queries, forwards and replies of this type from /var/log/pihole.log

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